Developed in conjunction with Ext-Joom.com

Institutes of Technology Ireland
Research & Innovation

Long Term Cell Storage for Drug Research

Biostór Ireland provides secure and certified real-time bio-storage of valuable biological materials for medical and scientific research; particularly in the healthcare, medical device, pharmaceutical and biopharmaceutical sectors. To meet the strategic objectives of on-going and future scientific and medical research, Biostór Ireland designed and constructed a technologically advanced repository for storage and distribution of biological materials. This facility complies with the requirements of an EU directive for the storage and distribution of human cells and tissues.

The overall objective for Biostór Ireland, from a commercial prospective, is to market and sell a new product, in the form of longer-term stored primary cells, directly to industry. This would enable those companies without owner access to laboratory animal facilities to directly avail of the stored cells for use in research. It would also have huge ethical benefits for clients companies due to the potential reduction in the overall number of animals used in research and development.

Established in 2009, the Ion Channel Biotechnology Centre (ICBC) is the commercialisation arm of the Smooth Muscle Research Centre at Dundalk Institute of Technology (DKIT). As an industry- engaged centre, the ICBC works on many collaborative projects with national and international companies and research institutes. The capabilities of the ICBC include laboratory facilities for electrophysiology, confocal microscopy, intracellular ion imaging, whole tissue set-ups, tension measuring and equipment to enable intracellular electrode recordings.

The research interests of the ICBC are focused on ion channels and their role in the physiological function of cells, which can be indicative of the overall health of cells and tissues.

Biostór Ireland engaged the ICBC to identify methods to improve the longer-term storage of primary cells for direct supply to industrial customers. The ICBC conducted analysis, using confocal microscopy and electrophysiology techniques, on the viability of cells that had been stored in a variety of conditions. The results of these analyses were reported to the company. As the initial findings looked promising, the ICBC and Biostor Ireland are continuing to collaborate to fully investigate the challenges and feasibility of producing this product in a commercially viable way.

This research was supported by Enterprise Ireland, initially through an Innovation Voucher project and subsequently through an Innovation Partnership project.

Testimonials

“From start to finish it has been a pleasure working with the group at ICBC. Their approach and follow up throughout the project was exceptional and the work was completed within a short time frame. We could badly do with a lot more places like ICBC/DkIT and there are many 3rd level institutes in the country that could benefit greatly from their professionalism. The result of the study was interesting and showed promising commercial benefit.”
Dr. Peadar MacGabhann - Managing Director, Biostór Ireland

“The idea of being able to store cells for long periods of time and sell them as a product is a worthy cause from both an ethical and business perspective. Biostór Ireland has a unique capability in this area and we look forward to a long term collaboration that will advance their business objectives while utilising the skills and expertise at the Ion Channel Biotechnology Centre. This helps ICBC fulfil its mandate in a real and meaningful fashion.”
Dr. Mary Earle - Centre Manager, Ion Channel Biotechnology Centre

Client: Biostor Ireland
Institution:
Dundalk Institute of Technology
Industry: Pharmaceuticals
National Priority Area: Therapeutic Synthesis, Formulation Processing and Drug Delivery

Head of Research
Dr. Tim McCormac
Dundalk Institute of Technology
Dublin Road
Dundalk, Co. Louth
Ireland
T: +353 (0)42 937 0459
E: This email address is being protected from spambots. You need JavaScript enabled to view it.

External Services Manager
Irene McCausland
Dundalk Institute of Technology
Dublin Road
Dundalk, Co. Louth
Ireland
T: +353 42 937 0403
E: This email address is being protected from spambots. You need JavaScript enabled to view it.

Ion Channel
Biotechnology Centre
Dr. Mary Earle
Dundalk Institute of Technology
Dublin Road
Dundalk, Louth
Ireland
T: +353 (0)42 937 0346
E: This email address is being protected from spambots. You need JavaScript enabled to view it.